Paradoxical effects of posterior intralaminar thalamic calretinin neurons on hippocampal seizure via distinct downstream circuits

Summary: Epilepsy is a circuit-level brain disorder characterized by hyperexcitatory seizures with unclear mechanisms.Here, we investigated the causal roles of calretinin (CR) neurons in the posterior intralaminar thalamic PEANUT BUTTER PROTEIN COOKIE nucleus (PIL) in hippocampal seizures.Using c-fos mapping and calcium fiber photometry, we found t

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Developing strategies to address barriers for tuberculosis case finding and retention in care among refugees in slums in Kampala, Uganda: a qualitative study using the COM-B model

Abstract Background Globally, displaced populations face an increased burden of tuberculosis (TB).Uganda is currently hosting unprecedented big numbers of refugees from the East African region.Recent evidence shows increased spread of multi-drug resistant TB (MDR-TB) across East Africa as a result of migrants from Somalia- a high MDR-TB prevalent c

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Variation of air condition parameters, in the conditions of the presence of carbon monoxide, in the duct of ventilation installations

Industrial ventilation and air conditioning systems aim to ensure the conditions of air purity and microclimate corresponding to the activity of man and the nature of the technological process.The parameters of the state of the air which are of interest for the technique of ventilation and air conditioning are: air temperature and humidity, atmosph

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