Summary: Epilepsy is a circuit-level brain disorder characterized by hyperexcitatory seizures with unclear mechanisms.Here, we investigated the causal roles of calretinin (CR) neurons in the posterior intralaminar thalamic PEANUT BUTTER PROTEIN COOKIE nucleus (PIL) in hippocampal seizures.Using c-fos mapping and calcium fiber photometry, we found t
The Effect of Hypothermic Machine Perfusion to Ameliorate Ischemia-Reperfusion Injury in Donor Organs
Hypothermic machine perfusion (HMP) has become the new gold standard in clinical donor kidney preservation and a promising novel strategy in higher risk donor livers in several countries.As shown by meta-analysis for the kidney, HMP decreases the risk of delayed graft function (DGF) and improves graft survival.For the liver, HMP immediately prior t
Developing strategies to address barriers for tuberculosis case finding and retention in care among refugees in slums in Kampala, Uganda: a qualitative study using the COM-B model
Abstract Background Globally, displaced populations face an increased burden of tuberculosis (TB).Uganda is currently hosting unprecedented big numbers of refugees from the East African region.Recent evidence shows increased spread of multi-drug resistant TB (MDR-TB) across East Africa as a result of migrants from Somalia- a high MDR-TB prevalent c
Analysis of the dynamics of changes in factor load models for predicting failures of a spacecraft
The paper considers the theoretical aspects of factor analysis as Foods Canned applied to the problem of predicting the failure-free operation of low-orbit communication satellites.The authors described the nature of the factors affecting the spacecraft during operation.The structure of the methodology for preparing data and creating factor load mo
Variation of air condition parameters, in the conditions of the presence of carbon monoxide, in the duct of ventilation installations
Industrial ventilation and air conditioning systems aim to ensure the conditions of air purity and microclimate corresponding to the activity of man and the nature of the technological process.The parameters of the state of the air which are of interest for the technique of ventilation and air conditioning are: air temperature and humidity, atmosph